| Reaction Details |
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 | Report a problem with these data |
| Target | SUMO-conjugating enzyme UBC9 |
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| Ligand | BDBM47311 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation |
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| IC50 | 9930±n/a nM |
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| Citation |  PubChem, PC AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| SUMO-conjugating enzyme UBC9 |
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| Name: | SUMO-conjugating enzyme UBC9 |
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| Synonyms: | UBC9 | UBC9_HUMAN | UBCE9 | UBE2I | ubiquitin-conjugating enzyme E2I |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 18011.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_4507785 |
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| Residue: | 158 |
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| Sequence: | MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKL
RMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELL
NEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
|
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|
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| BDBM47311 |
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| n/a |
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| Name | BDBM47311 |
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| Synonyms: | 2-[(4-chlorobenzyl)sulfanyl]-6-oxo-4-(2-thienyl)-1,6-dihydro-5-pyrimidinecarbonitrile | 2-[(4-chlorobenzyl)thio]-4-keto-6-(2-thienyl)-1H-pyrimidine-5-carbonitrile | 2-[(4-chlorophenyl)methylsulfanyl]-4-oxidanylidene-6-thiophen-2-yl-1H-pyrimidine-5-carbonitrile | 2-[(4-chlorophenyl)methylsulfanyl]-4-oxo-6-thiophen-2-yl-1H-pyrimidine-5-carbonitrile | 2-[(4-chlorophenyl)methylthio]-4-oxo-6-thiophen-2-yl-1H-pyrimidine-5-carbonitrile | MLS000705749 | SMR000231786 | cid_1234393 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H10ClN3OS2 |
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| Mol. Mass. | 359.853 |
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| SMILES | Clc1ccc(CSc2nc(-c3cccs3)c(C#N)c(=O)[nH]2)cc1 |
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| Structure | 
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