| Reaction Details |
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 | Report a problem with these data |
| Target | Cell division control protein 42 homolog |
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| Ligand | BDBM54612 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype protein |
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| EC50 | 30000±n/a nM |
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| Citation |  PubChem, PC Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype protein PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Cell division control protein 42 homolog |
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| Name: | Cell division control protein 42 homolog |
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| Synonyms: | CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa) |
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| Type: | PROTEIN |
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| Mol. Mass.: | 21258.36 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_652970 |
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| Residue: | 191 |
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| Sequence: | MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG
QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR
DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP
EPKKSRRCVLL
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| BDBM54612 |
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| n/a |
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| Name | BDBM54612 |
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| Synonyms: | 2-[4-[bis(fluoranyl)methylsulfonyl]phenyl]-5-(4-bromophenyl)-3-phenyl-3,4-dihydropyrazole | 3-(4-bromophenyl)-1-[4-(difluoromethylsulfonyl)phenyl]-5-phenyl-2-pyrazoline | 5-(4-bromophenyl)-2-[4-(difluoromethylsulfonyl)phenyl]-3-phenyl-3,4-dihydropyrazole | UNM-0000305851 | cid_2865099 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H17BrF2N2O2S |
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| Mol. Mass. | 491.348 |
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| SMILES | FC(F)S(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccccc1)c1ccc(Br)cc1 |c:14| |
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| Structure | 
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