| Reaction Details |
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 | Report a problem with these data |
| Target | Cell division control protein 42 homolog |
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| Ligand | BDBM54687 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Additional SAR compounds tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant |
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| Ki | 2880±n/a nM |
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| Citation |  PubChem, PC Additional SAR compounds tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Cell division control protein 42 homolog |
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| Name: | Cell division control protein 42 homolog |
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| Synonyms: | CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa) |
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| Type: | PROTEIN |
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| Mol. Mass.: | 21258.36 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_652970 |
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| Residue: | 191 |
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| Sequence: | MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG
QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR
DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP
EPKKSRRCVLL
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| BDBM54687 |
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| n/a |
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| Name | BDBM54687 |
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| Synonyms: | 2-amino-5-benzoyl-1-butylsulfonyl-4-(3,4,5-trimethoxyphenyl)-3-pyrrolecarbonitrile | 2-amino-5-benzoyl-1-butylsulfonyl-4-(3,4,5-trimethoxyphenyl)pyrrole-3-carbonitrile | 2-azanyl-1-butylsulfonyl-5-(phenylcarbonyl)-4-(3,4,5-trimethoxyphenyl)pyrrole-3-carbonitrile | UNM-0000305777 | cid_25220928 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H27N3O6S |
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| Mol. Mass. | 497.563 |
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| SMILES | CCCCS(=O)(=O)n1c(N)c(C#N)c(c1C(=O)c1ccccc1)-c1cc(OC)c(OC)c(OC)c1 |
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| Structure | 
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