| Reaction Details |
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 | Report a problem with these data |
| Target | Ras-related protein Rab-2A |
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| Ligand | BDBM54580 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype |
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| EC50 | 30000±n/a nM |
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| Citation |  PubChem, PC Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Ras-related protein Rab-2A |
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| Name: | Ras-related protein Rab-2A |
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| Synonyms: | RAB2 | RAB2A | RAB2A_CANLF | Ras-related protein Rab-2A. |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23545.28 |
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| Organism: | Canis lupus familiaris |
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| Description: | gi_46577642 |
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| Residue: | 212 |
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| Sequence: | MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIW
DTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNK
SDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINN
EANGIKIGPQHAATNATHAGNQGGQQAGGGCC
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| BDBM54580 |
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| n/a |
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| Name | BDBM54580 |
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| Synonyms: | 3-[3-[4-(dimethylamino)phenyl]-1,2,4-oxadiazol-5-yl]-1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-1-propanone | 3-[3-[4-(dimethylamino)phenyl]-1,2,4-oxadiazol-5-yl]-1-[4-(2,5-dimethylphenyl)piperazin-1-yl]propan-1-one | 3-[3-[4-(dimethylamino)phenyl]-1,2,4-oxadiazol-5-yl]-1-[4-(2,5-dimethylphenyl)piperazino]propan-1-one | KUC103409N | UNM-0000306126 | cid_42628047 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H31N5O2 |
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| Mol. Mass. | 433.5459 |
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| SMILES | CN(C)c1ccc(cc1)-c1noc(CCC(=O)N2CCN(CC2)c2cc(C)ccc2C)n1 |
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| Structure | 
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