Reaction Details |
| Report a problem with these data |
Target | Ras-related protein Rab-2A |
---|
Ligand | BDBM54584 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype |
---|
Ki | 160±n/a nM |
---|
Citation | PubChem, PC Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype PubChem Bioassay(2009)[AID] |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
Ras-related protein Rab-2A |
---|
Name: | Ras-related protein Rab-2A |
Synonyms: | RAB2 | RAB2A | RAB2A_CANLF | Ras-related protein Rab-2A. |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 23545.28 |
Organism: | Canis lupus familiaris |
Description: | gi_46577642 |
Residue: | 212 |
Sequence: | MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIW
DTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNK
SDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINN
EANGIKIGPQHAATNATHAGNQGGQQAGGGCC
|
|
|
BDBM54584 |
---|
n/a |
---|
Name | BDBM54584 |
Synonyms: | 1-[4-(2,5-dimethylphenyl)-1-piperidinyl]-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-propanone | 1-[4-(2,5-dimethylphenyl)piperidin-1-yl]-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propan-1-one | 1-[4-(2,5-dimethylphenyl)piperidino]-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propan-1-one | KUC103432N | UNM-0000306151 | cid_44143707 |
Type | Small organic molecule |
Emp. Form. | C25H29N3O3 |
Mol. Mass. | 419.5161 |
SMILES | COc1ccc(cc1)-c1noc(CCC(=O)N2CCC(CC2)c2cc(C)ccc2C)n1 |
Structure |
|