| Reaction Details |
|---|
 | Report a problem with these data |
| Target | GTPase KRas [1-37] |
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| Ligand | BDBM54685 |
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| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype |
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| Ki | 5850±n/a nM |
|---|
| Citation |  PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| GTPase KRas [1-37] |
|---|
| Name: | GTPase KRas [1-37] |
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| Synonyms: | ras protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 4034.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_190938 |
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| Residue: | 37 |
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| Sequence: | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
|
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|
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| BDBM54685 |
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| n/a |
|---|
| Name | BDBM54685 |
|---|
| Synonyms: | 7-bromanyl-3-[3-(oxidanylamino)-1H-indol-2-yl]indol-2-one | 7-bromo-3-[3-(hydroxyamino)-1H-indol-2-yl]-2-indolone | 7-bromo-3-[3-(hydroxyamino)-1H-indol-2-yl]indol-2-one | UNM-0000305775 | cid_11846148 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H10BrN3O2 |
|---|
| Mol. Mass. | 356.174 |
|---|
| SMILES | ONc1c([nH]c2ccccc12)C1=c2cccc(Br)c2=NC1=O |c:13,21| |
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| Structure | 
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|---|
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