| Reaction Details |
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 | Report a problem with these data |
| Target | Ras-related C3 botulinum toxin substrate 1 |
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| Ligand | BDBM54689 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype |
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| EC50 | 9840±n/a nM |
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| Citation |  PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Ras-related C3 botulinum toxin substrate 1 |
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| Name: | Ras-related C3 botulinum toxin substrate 1 |
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| Synonyms: | RAC1_MOUSE | Rac1 | Rac1 protein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 21455.91 |
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| Organism: | Mus musculus |
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| Description: | EBI_101485 |
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| Residue: | 192 |
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| Sequence: | MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL
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| BDBM54689 |
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| n/a |
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| Name | BDBM54689 |
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| Synonyms: | 2-amino-5-benzoyl-4-(5-bromo-3-pyridinyl)-1-(4-methoxyphenyl)sulfonyl-3-pyrrolecarbonitrile | 2-amino-5-benzoyl-4-(5-bromo-3-pyridyl)-1-(4-methoxyphenyl)sulfonyl-pyrrole-3-carbonitrile | 2-amino-5-benzoyl-4-(5-bromopyridin-3-yl)-1-(4-methoxyphenyl)sulfonylpyrrole-3-carbonitrile | 2-azanyl-4-(5-bromanylpyridin-3-yl)-1-(4-methoxyphenyl)sulfonyl-5-(phenylcarbonyl)pyrrole-3-carbonitrile | UNM-0000305779 | cid_25220930 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H17BrN4O4S |
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| Mol. Mass. | 537.385 |
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| SMILES | COc1ccc(cc1)S(=O)(=O)n1c(N)c(C#N)c(c1C(=O)c1ccccc1)-c1cncc(Br)c1 |
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| Structure | 
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