Reaction Details |
| Report a problem with these data |
Target | Ras-related C3 botulinum toxin substrate 1 |
---|
Ligand | BDBM54707 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype |
---|
EC50 | 30000±n/a nM |
---|
Citation | PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype PubChem Bioassay(2009)[AID] |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
Ras-related C3 botulinum toxin substrate 1 |
---|
Name: | Ras-related C3 botulinum toxin substrate 1 |
Synonyms: | RAC1_MOUSE | Rac1 | Rac1 protein |
Type: | PROTEIN |
Mol. Mass.: | 21455.91 |
Organism: | Mus musculus |
Description: | EBI_101485 |
Residue: | 192 |
Sequence: | MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL
|
|
|
BDBM54707 |
---|
n/a |
---|
Name | BDBM54707 |
Synonyms: | 2-[(3E)-6-fluoranyl-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1-yl]ethanoic acid | 2-[(3E)-6-fluoro-2-methyl-3-(4-methylsulfinylbenzylidene)inden-1-yl]acetic acid | 2-[(3E)-6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]-1-indenyl]acetic acid | 2-[(3E)-6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1-yl]acetic acid | UNM-0000306136 | cid_1548885 |
Type | Small organic molecule |
Emp. Form. | C20H17FO3S |
Mol. Mass. | 356.411 |
SMILES | CC1=C(CC(O)=O)c2cc(F)ccc2\C1=C\c1ccc(cc1)S(C)=O |c:1| |
Structure |
|