Ki Summary

Reaction Details

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Target

Ras-related C3 botulinum toxin substrate 1

Ligand

BDBM54691

Substrate/Competitor

n/a

Meas. Tech.

Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype

7040±n/a nM

Citation

PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Ras-related C3 botulinum toxin substrate 1

Name:

Ras-related C3 botulinum toxin substrate 1

Synonyms:

RAC1_MOUSE | Rac1 | Rac1 protein

Type:

PROTEIN

Mol. Mass.:

21455.91

Organism:

Mus musculus

Description:

EBI_101485

Residue:

192

Sequence:

MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL

BDBM54691

n/a

Name

BDBM54691

Synonyms:

2-amino-5-benzoyl-1-(2,4,6-triisopropylphenyl)sulfonyl-4-(3,4,5-trimethoxyphenyl)pyrrole-3-carbonitrile | 2-amino-5-benzoyl-4-(3,4,5-trimethoxyphenyl)-1-[2,4,6-tri(propan-2-yl)phenyl]sulfonyl-3-pyrrolecarbonitrile | 2-amino-5-benzoyl-4-(3,4,5-trimethoxyphenyl)-1-[2,4,6-tri(propan-2-yl)phenyl]sulfonylpyrrole-3-carbonitrile | 2-azanyl-5-(phenylcarbonyl)-4-(3,4,5-trimethoxyphenyl)-1-[2,4,6-tri(propan-2-yl)phenyl]sulfonyl-pyrrole-3-carbonitrile | UNM-0000305781 | cid_25220932

Type

Small organic molecule

Emp. Form.

C36H41N3O6S

Mol. Mass.

643.792

SMILES

COc1cc(cc(OC)c1OC)-c1c(C#N)c(N)n(c1C(=O)c1ccccc1)S(=O)(=O)c1c(cc(cc1C(C)C)C(C)C)C(C)C

Structure