| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ras-related protein Rab-7a |
|---|
| Ligand | BDBM13063 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype |
|---|
| EC50 | 30000±n/a nM |
|---|
| Citation |  PubChem, PC Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Ras-related protein Rab-7a |
|---|
| Name: | Ras-related protein Rab-7a |
|---|
| Synonyms: | GTP-binding protein (rab7) | RAB7 | RAB7A | RAB7A_CANLF |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 23519.50 |
|---|
| Organism: | Canis lupus familiaris |
|---|
| Description: | gi_164058 |
|---|
| Residue: | 207 |
|---|
| Sequence: | MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQ
IWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPF
VVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEV
ELYNEFPEPIKLDKNDRAKTSAESCSC
|
|
|
|---|
| BDBM13063 |
|---|
| n/a |
|---|
| Name | BDBM13063 |
|---|
| Synonyms: | 4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sulfonamide | Bextra | CHEMBL865 | VLX | Valdecoxib | cid_119607 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H14N2O3S |
|---|
| Mol. Mass. | 314.359 |
|---|
| SMILES | Cc1onc(c1-c1ccc(cc1)S(N)(=O)=O)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
