Reaction Details |
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Target | GTPase KRas [1-37] |
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Ligand | BDBM54544 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant |
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EC50 | 30000±n/a nM |
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Citation | PubChem, PC Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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GTPase KRas [1-37] |
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Name: | GTPase KRas [1-37] |
Synonyms: | ras protein |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 4034.04 |
Organism: | Homo sapiens (Human) |
Description: | gi_190938 |
Residue: | 37 |
Sequence: | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
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BDBM54544 |
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n/a |
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Name | BDBM54544 |
Synonyms: | 3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-(4-phenyl-1-piperazinyl)-1-propanone | 3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-(4-phenylpiperazin-1-yl)propan-1-one | 3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-(4-phenylpiperazino)propan-1-one | KUC103350N | UNM-0000306064 | cid_22107972 |
Type | Small organic molecule |
Emp. Form. | C22H24N4O3 |
Mol. Mass. | 392.451 |
SMILES | COc1ccc(cc1)-c1noc(CCC(=O)N2CCN(CC2)c2ccccc2)n1 |
Structure |
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