Reaction Details |
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Target | GTPase KRas [1-37] |
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Ligand | BDBM54706 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant |
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EC50 | 30000±n/a nM |
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Comments | Extracted from aid = 2043 and tid = 2 |
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Citation | PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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GTPase KRas [1-37] |
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Name: | GTPase KRas [1-37] |
Synonyms: | ras protein |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 4034.04 |
Organism: | Homo sapiens (Human) |
Description: | gi_190938 |
Residue: | 37 |
Sequence: | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
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BDBM54706 |
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n/a |
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Name | BDBM54706 |
Synonyms: | 2-(6-methoxy-2-naphthalenyl)acetic acid | 2-(6-methoxy-2-naphthyl)acetic acid | 2-(6-methoxynaphthalen-2-yl)acetic acid | 2-(6-methoxynaphthalen-2-yl)ethanoic acid | UNM-0000306103 | US11459295, Compound DesmethylNaproxen 10 | cid_32176 |
Type | Small organic molecule |
Emp. Form. | C13H12O3 |
Mol. Mass. | 216.2326 |
SMILES | COc1ccc2cc(CC(O)=O)ccc2c1 |
Structure |
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