| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ras-related protein Rab-2A |
|---|
| Ligand | BDBM54693 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype |
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| EC50 | 1738±n/a nM |
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| Citation |  PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Ras-related protein Rab-2A |
|---|
| Name: | Ras-related protein Rab-2A |
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| Synonyms: | RAB2 | RAB2A | RAB2A_CANLF | Ras-related protein Rab-2A. |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23545.28 |
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| Organism: | Canis lupus familiaris |
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| Description: | gi_46577642 |
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| Residue: | 212 |
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| Sequence: | MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIW
DTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNK
SDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINN
EANGIKIGPQHAATNATHAGNQGGQQAGGGCC
|
|
|
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| BDBM54693 |
|---|
| n/a |
|---|
| Name | BDBM54693 |
|---|
| Synonyms: | UNM-0000305812 | cid_23675324 | sodium;(2R)-2-(6-methoxy-2-naphthalenyl)propanoate | sodium;(2R)-2-(6-methoxy-2-naphthyl)propionate | sodium;(2R)-2-(6-methoxynaphthalen-2-yl)propanoate |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C14H13O3 |
|---|
| Mol. Mass. | 229.2518 |
|---|
| SMILES | COc1ccc2cc(ccc2c1)[C@@H](C)C([O-])=O |
|---|
| Structure | 
|
|---|
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