Reaction Details |
| Report a problem with these data |
Target | GTPase KRas [1-37] |
---|
Ligand | BDBM11639 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype |
---|
EC50 | 30000±n/a nM |
---|
Citation | PubChem, PC Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype PubChem Bioassay(2009)[AID] |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
GTPase KRas [1-37] |
---|
Name: | GTPase KRas [1-37] |
Synonyms: | ras protein |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 4034.04 |
Organism: | Homo sapiens (Human) |
Description: | gi_190938 |
Residue: | 37 |
Sequence: | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
|
|
|
BDBM11639 |
---|
n/a |
---|
Name | BDBM11639 |
Synonyms: | 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide | CHEMBL118 | CLX | Celebrex | Celecoxib | US10322118, Urea-Based Scaffold Entry 9 | US11478464, Compound Celecoxib | US11786535, Compound Celecoxib | US8741944, Comparative Compound | US9388139, Celecoxib | cid_2662 |
Type | Small organic molecule |
Emp. Form. | C17H14F3N3O2S |
Mol. Mass. | 381.372 |
SMILES | Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F |
Structure |
|