| Reaction Details |
|---|
 | Report a problem with these data |
| Target | GTPase KRas [1-37] |
|---|
| Ligand | BDBM54651 |
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| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant |
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| EC50 | 30000±n/a nM |
|---|
| Citation |  PubChem, PC Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| GTPase KRas [1-37] |
|---|
| Name: | GTPase KRas [1-37] |
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| Synonyms: | ras protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 4034.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_190938 |
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| Residue: | 37 |
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| Sequence: | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
|
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|
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| BDBM54651 |
|---|
| n/a |
|---|
| Name | BDBM54651 |
|---|
| Synonyms: | 4-(3,5-diphenyl-2-pyrazolin-1-yl)benzenesulfonamide | 4-(3,5-diphenyl-3,4-dihydropyrazol-2-yl)benzenesulfonamide | KUC103427N | UNM-0000306146 | cid_2837695 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H19N3O2S |
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| Mol. Mass. | 377.459 |
|---|
| SMILES | NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccccc1)c1ccccc1 |c:12| |
|---|
| Structure | 
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|---|
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