| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ras-related C3 botulinum toxin substrate 1 |
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| Ligand | BDBM54613 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype |
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| EC50 | 30000±n/a nM |
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| Citation |  PubChem, PC Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Ras-related C3 botulinum toxin substrate 1 |
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| Name: | Ras-related C3 botulinum toxin substrate 1 |
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| Synonyms: | RAC1_MOUSE | Rac1 | Rac1 protein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 21455.91 |
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| Organism: | Mus musculus |
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| Description: | EBI_101485 |
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| Residue: | 192 |
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| Sequence: | MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL
|
|
|
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| BDBM54613 |
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| n/a |
|---|
| Name | BDBM54613 |
|---|
| Synonyms: | 3-(4-methoxyphenyl)-2-(4-nitrophenyl)-5-phenyl-3,4-dihydropyrazole | 5-(4-methoxyphenyl)-1-(4-nitrophenyl)-3-phenyl-2-pyrazoline | UNM-0000305852 | cid_2865225 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C22H19N3O3 |
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| Mol. Mass. | 373.4046 |
|---|
| SMILES | COc1ccc(cc1)C1C[C-](N=[N+]1c1ccc(cc1)[N+]([O-])=O)c1ccccc1 |c:12| |
|---|
| Structure | 
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|---|
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