| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Bcl-2-like protein 10 [11-204] |
|---|
| Ligand | BDBM33173 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B |
|---|
| EC50 | 2900±n/a nM |
|---|
| Citation |  PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Bcl-2-like protein 10 [11-204] |
|---|
| Name: | Bcl-2-like protein 10 [11-204] |
|---|
| Synonyms: | Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 21981.77 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_23396469 |
|---|
| Residue: | 194 |
|---|
| Sequence: | MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGY
PGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQ
EGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSC
LLTTAFIYLWTRLL
|
|
|
|---|
| BDBM33173 |
|---|
| n/a |
|---|
| Name | BDBM33173 |
|---|
| Synonyms: | (5E)-5-(2-furanylmethylidene)-3-phenyl-2-sulfanylidene-4-imidazolidinone | (5E)-5-(2-furfurylidene)-3-phenyl-2-thioxo-4-imidazolidinone | (5E)-5-(furan-2-ylmethylidene)-3-phenyl-2-sulfanylidene-imidazolidin-4-one | (5E)-5-(furan-2-ylmethylidene)-3-phenyl-2-sulfanylideneimidazolidin-4-one | MLS000693194 | SMR000284616 | cid_5751662 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H10N2O2S |
|---|
| Mol. Mass. | 270.306 |
|---|
| SMILES | O=C1N(C(=S)NC1=Cc1ccco1)c1ccccc1 |w:7.8| |
|---|
| Structure | 
|
|---|
Search and Browse
