| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 10 [11-204] |
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| Ligand | BDBM32275 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B |
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| EC50 | 13470±n/a nM |
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| Citation |  PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Bcl-2-like protein 10 [11-204] |
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| Name: | Bcl-2-like protein 10 [11-204] |
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| Synonyms: | Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 21981.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_23396469 |
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| Residue: | 194 |
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| Sequence: | MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGY
PGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQ
EGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSC
LLTTAFIYLWTRLL
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|
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| BDBM32275 |
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| n/a |
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| Name | BDBM32275 |
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| Synonyms: | (4-Chloro-6-morpholin-4-yl-[1,3,5]triazin-2-yl)-pyridin-3-ylmethyl-amine | (4-chloro-6-morpholino-s-triazin-2-yl)-(3-pyridylmethyl)amine | 4-chloranyl-6-morpholin-4-yl-N-(pyridin-3-ylmethyl)-1,3,5-triazin-2-amine | 4-chloro-6-(4-morpholinyl)-N-(3-pyridinylmethyl)-1,3,5-triazin-2-amine | 4-chloro-6-morpholin-4-yl-N-(pyridin-3-ylmethyl)-1,3,5-triazin-2-amine | MLS000121154 | SMR000118549 | cid_684642 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H15ClN6O |
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| Mol. Mass. | 306.751 |
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| SMILES | Clc1nc(NCc2cccnc2)nc(n1)N1CCOCC1 |
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| Structure | 
|
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