| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 10 [11-204] |
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| Ligand | BDBM33183 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B |
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| EC50 | 36540±n/a nM |
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| Citation |  PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Bcl-2-like protein 10 [11-204] |
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| Name: | Bcl-2-like protein 10 [11-204] |
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| Synonyms: | Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 21981.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_23396469 |
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| Residue: | 194 |
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| Sequence: | MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGY
PGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQ
EGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSC
LLTTAFIYLWTRLL
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| BDBM33183 |
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| n/a |
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| Name | BDBM33183 |
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| Synonyms: | 5-[[5-(5-chloranyl-2-nitro-phenyl)furan-2-yl]methylidene]-1,3-diazinane-2,4,6-trione | 5-[[5-(5-chloro-2-nitro-phenyl)-2-furyl]methylene]barbituric acid | 5-[[5-(5-chloro-2-nitrophenyl)-2-furanyl]methylidene]-1,3-diazinane-2,4,6-trione | 5-[[5-(5-chloro-2-nitrophenyl)furan-2-yl]methylidene]-1,3-diazinane-2,4,6-trione | MLS000689180 | SMR000283261 | cid_3122089 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H8ClN3O6 |
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| Mol. Mass. | 361.694 |
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| SMILES | [O-]c1[nH]c(=O)[nH]c(=O)c1[CH+]c1ccc(o1)-c1cc(Cl)ccc1[N+]([O-])=O |
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| Structure | 
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