| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 10 [11-204] |
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| Ligand | BDBM33168 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B |
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| EC50 | 1460±n/a nM |
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| Citation |  PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Bcl-2-like protein 10 [11-204] |
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| Name: | Bcl-2-like protein 10 [11-204] |
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| Synonyms: | Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 21981.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_23396469 |
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| Residue: | 194 |
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| Sequence: | MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGY
PGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQ
EGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSC
LLTTAFIYLWTRLL
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|
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| BDBM33168 |
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| n/a |
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| Name | BDBM33168 |
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| Synonyms: | MLS000708356 | N-[5-[(4-chloranylphenoxy)methyl]-1,3,4-thiadiazol-2-yl]furan-2-carboxamide | N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-2-furamide | N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-2-furancarboxamide | N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]furan-2-carboxamide | SMR000287823 | cid_921149 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H10ClN3O3S |
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| Mol. Mass. | 335.766 |
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| SMILES | Clc1ccc(OCc2nnc(NC(=O)c3ccco3)s2)cc1 |
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| Structure | 
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