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TargetBcl-2-like protein 10 [11-204]
LigandBDBM33087
Substrate/Competitorn/a
Meas. Tech.Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B
EC50 31590±n/a nM
Citation PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Bcl-2-like protein 10 [11-204]
Name:Bcl-2-like protein 10 [11-204]
Synonyms:Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA
Type:Enzyme Catalytic Domain
Mol. Mass.:21981.77
Organism:Homo sapiens (Human)
Description:gi_23396469
Residue:194
Sequence:
MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGY
PGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQ
EGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSC
LLTTAFIYLWTRLL
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  Blast E-value cutoff:
BDBM33087
n/a
NameBDBM33087
Synonyms:2,3-bis(2-furanyl)-N-(phenylmethyl)-6-quinoxalinecarboxamide | 2,3-bis(furan-2-yl)-N-(phenylmethyl)quinoxaline-6-carboxamide | MLS000534716 | N-benzyl-2,3-bis(2-furyl)quinoxaline-6-carboxamide | N-benzyl-2,3-bis(furan-2-yl)quinoxaline-6-carboxamide | N-benzyl-2,3-di-2-furyl-6-quinoxalinecarboxamide | SMR000142133 | cid_1329592
TypeSmall organic molecule
Emp. Form.C24H17N3O3
Mol. Mass.395.4101
SMILESO=C(NCc1ccccc1)c1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1
Structure
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