| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 10 [11-204] |
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| Ligand | BDBM33165 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B |
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| EC50 | 610±n/a nM |
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| Citation |  PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Bcl-2-like protein 10 [11-204] |
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| Name: | Bcl-2-like protein 10 [11-204] |
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| Synonyms: | Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 21981.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_23396469 |
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| Residue: | 194 |
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| Sequence: | MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGY
PGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQ
EGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSC
LLTTAFIYLWTRLL
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| BDBM33165 |
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| n/a |
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| Name | BDBM33165 |
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| Synonyms: | 3-chloranyl-4-(3-methoxyphenoxy)-1-(4-methoxyphenyl)pyrrole-2,5-dione | 3-chloro-4-(3-methoxyphenoxy)-1-(4-methoxyphenyl)-1H-pyrrole-2,5-dione | 3-chloro-4-(3-methoxyphenoxy)-1-(4-methoxyphenyl)-3-pyrroline-2,5-quinone | 3-chloro-4-(3-methoxyphenoxy)-1-(4-methoxyphenyl)pyrrole-2,5-dione | MLS000676199 | SMR000271936 | cid_2791433 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14ClNO5 |
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| Mol. Mass. | 359.76 |
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| SMILES | COc1ccc(cc1)N1C(=O)C(Cl)=C(Oc2cccc(OC)c2)C1=O |t:13| |
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| Structure | 
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