| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 10 [11-204] |
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| Ligand | BDBM33198 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B |
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| EC50 | 920±n/a nM |
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| Citation |  PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Bcl-2-like protein 10 [11-204] |
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| Name: | Bcl-2-like protein 10 [11-204] |
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| Synonyms: | Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 21981.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_23396469 |
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| Residue: | 194 |
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| Sequence: | MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGY
PGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQ
EGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSC
LLTTAFIYLWTRLL
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|
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| BDBM33198 |
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| n/a |
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| Name | BDBM33198 |
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| Synonyms: | MLS001001946 | N-[4-(4-phenyl-2-thioxo-4-imidazolin-1-yl)phenyl]acetamide | N-[4-(5-phenyl-2-sulfanylidene-1H-imidazol-3-yl)phenyl]acetamide | N-[4-(5-phenyl-2-sulfanylidene-1H-imidazol-3-yl)phenyl]ethanamide | SMR000353339 | cid_719482 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15N3OS |
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| Mol. Mass. | 309.386 |
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| SMILES | CC(=O)Nc1ccc(cc1)-n1cc([nH]c1=S)-c1ccccc1 |
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| Structure | 
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