Reaction Details | |||
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Target | Bcl-2-like protein 10 [11-204] | ||
Ligand | BDBM33197 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B | ||
EC50 | 24360±n/a nM | ||
Citation | PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B PubChem Bioassay(2009)[AID] | ||
More Info.: | Get all data from this article, Solution Info, Assay Method | ||
Bcl-2-like protein 10 [11-204] | |||
Name: | Bcl-2-like protein 10 [11-204] | ||
Synonyms: | Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 21981.77 | ||
Organism: | Homo sapiens (Human) | ||
Description: | gi_23396469 | ||
Residue: | 194 | ||
Sequence: |
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BDBM33197 | |||
n/a | |||
Name | BDBM33197 | ||
Synonyms: | 1-(2-methoxyphenyl)-5-phenyl-4-imidazoline-2-thione | 3-(2-methoxyphenyl)-4-phenyl-1H-imidazole-2-thione | MLS001007615 | SMR000384694 | cid_4962043 | ||
Type | Small organic molecule | ||
Emp. Form. | C16H14N2OS | ||
Mol. Mass. | 282.36 | ||
SMILES | COc1ccccc1-n1c(c[nH]c1=S)-c1ccccc1 |(3.08,-1.57,;4.41,-.8,;5.75,-1.57,;5.75,-3.11,;7.08,-3.88,;8.41,-3.11,;8.41,-1.57,;7.08,-.8,;7.08,.74,;8.33,1.64,;7.85,3.11,;6.31,3.11,;5.84,1.64,;4.37,1.17,;9.79,1.17,;10.11,-.34,;11.58,-.81,;12.72,.22,;12.4,1.72,;10.94,2.2,)| | ||
Structure |