Ki Summary

Reaction Details

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Target

Bcl-2-related protein A1

Ligand

BDBM33097

Substrate/Competitor

n/a

Meas. Tech.

Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1

EC50

170±n/a nM

Citation

PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1 PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Bcl-2-related protein A1

Name:

Bcl-2-related protein A1

Synonyms:

Type:

Apoptosis regulator protein

Mol. Mass.:

20130.01

Organism:

Homo sapiens (Human)

Description:

n/a

Residue:

175

Sequence:

MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVN
VVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISY
FVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC

BDBM33097

n/a

Name

BDBM33097

Synonyms:

3-[[7-(1,3-benzothiazol-2-ylsulfanyl)-4-nitro-2,1,3-benzoxadiazol-5-yl]amino]propyl acetate | 3-[[7-(1,3-benzothiazol-2-ylsulfanyl)-4-nitro-2,1,3-benzoxadiazol-5-yl]amino]propyl ethanoate | MLS000521052 | SMR000131461 | acetic acid 3-[[7-(1,3-benzothiazol-2-ylthio)-4-nitro-2,1,3-benzoxadiazol-5-yl]amino]propyl ester | acetic acid 3-[[7-(1,3-benzothiazol-2-ylthio)-4-nitro-benzofurazan-5-yl]amino]propyl ester | cid_11957209

Type

Small organic molecule

Emp. Form.

C18H15N5O5S2

Mol. Mass.

445.472

SMILES

CC(=O)OCCCNc1cc(Sc2nc3ccccc3s2)c2nonc2c1[N+]([O-])=O

Structure