| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 2 |
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| Ligand | BDBM33188 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W |
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| EC50 | 1310±n/a nM |
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| Citation |  PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Bcl-2-like protein 2 |
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| Name: | Bcl-2-like protein 2 |
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| Synonyms: | Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271 |
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| Type: | Protein |
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| Mol. Mass.: | 20742.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 193 |
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| Sequence: | MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRT
FSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVG
QVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVAL
GALVTVGAFFASK
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|
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| BDBM33188 |
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| n/a |
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| Name | BDBM33188 |
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| Synonyms: | 2-({7-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]-4-nitro-2,1,3-benzoxadiazol-5-yl}amino)ethanol | 2-[[7-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]-4-nitro-2,1,3-benzoxadiazol-5-yl]amino]ethanol | 2-[[7-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]-4-nitro-2,1,3-benzoxadiazol-5-yl]amino]ethanol | 2-[[7-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]-4-nitro-benzofurazan-5-yl]amino]ethanol | MLS000674024 | SMR000311302 | cid_16195158 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H10N6O4S2 |
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| Mol. Mass. | 354.365 |
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| SMILES | Cc1nnc(Sc2cc(NCCO)c([N+]([O-])=O)c3nonc23)s1 |
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| Structure | 
|
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