| Reaction Details |
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 | Report a problem with these data |
| Target | Amyloid-beta A4 precursor protein-binding family A member 1 |
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| Ligand | BDBM33077 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | uHTS Homogeneous Terbium Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay |
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| IC50 | 507±n/a nM |
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| Citation |  PubChem, PC uHTS Homogeneous Terbium Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Amyloid-beta A4 precursor protein-binding family A member 1 |
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| Name: | Amyloid-beta A4 precursor protein-binding family A member 1 |
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| Synonyms: | APBA1_RAT | Apba1 | Mint1 | X11 | neuronal munc18-1 binding protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 92603.32 |
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| Organism: | Rattus norvegicus |
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| Description: | gi_2625023 |
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| Residue: | 839 |
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| Sequence: | MNHLEGSAEVEVADEAPGGEVNESVEADLEHPEVEEEQQPSPPPPAGHAPEDHRAHPAPP
PPPPPQEEEEERGECLARSASTESGFHNHTDTAEGDVLAAARDGYEAERAQDADDESAYA
VQYRPEAEEYTEQAEAEHAEAAQRRALPNHLHFHSLEHEEAMNAAYSGYVYTHRLFHRAE
DEPYAEPYADYGGLQEHVYEEIGDAPELEARDGLRLYERERDEAAAYRQEALGARLHHYD
ERSDGESDSPEKEAEFAPYPRMDSYEQEEDIDQIVAEVKQSMSSQSLDKAAEDMPEAEQD
LERAPTPGGGHPDSPGLPAPAGQQQRVVGTPGGSEVGQRYSKEKRDAISLAIKDIKEAIE
EVKTRTIRSPYTPDEPKEPIWVMRQDISPTRDCDDQRPVDGDSPSPGSSSPLGAESSITP
LHPGDPTEASTNKESRKSLASFPTYVEVPGPCDPEDLIDGIIFAANYLGSTQLLSDKTPS
KNVRMMQAQEAVSRIKTAQKLAKSRKKAPEGESQPMTEVDLFISTQRIKVLNADTQEPMM
DHPLRTISYIADIGNIVVLMARRRMPRSNSQENVEASHPSQDAKRQYKMICHVFESEDAQ
LIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDLLNTQDMYNDDLIHFSKSENCKDVF
IEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLP
LSTCQSIIKGLKNQSRVKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAE
RGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI
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| BDBM33077 |
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| n/a |
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| Name | BDBM33077 |
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| Synonyms: | 1-[2,3-bis(2-furanyl)-6-quinoxalinyl]-3-(3-hydroxypropyl)urea | 1-[2,3-bis(2-furyl)quinoxalin-6-yl]-3-(3-hydroxypropyl)urea | 1-[2,3-bis(furan-2-yl)quinoxalin-6-yl]-3-(3-hydroxypropyl)urea | 1-[2,3-bis(furan-2-yl)quinoxalin-6-yl]-3-(3-oxidanylpropyl)urea | MLS000534763 | N-(2,3-di-2-furyl-6-quinoxalinyl)-N'-(3-hydroxypropyl)urea | SMR000142219 | cid_2301472 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18N4O4 |
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| Mol. Mass. | 378.3813 |
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| SMILES | OCCCNC(=O)Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1 |
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| Structure | 
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