| Reaction Details |
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 | Report a problem with these data |
| Target | Amyloid-beta A4 precursor protein-binding family A member 1 |
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| Ligand | BDBM54734 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | uHTS Homogeneous Terbium Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay |
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| IC50 | 2100±n/a nM |
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| Citation |  PubChem, PC uHTS Homogeneous Terbium Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Amyloid-beta A4 precursor protein-binding family A member 1 |
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| Name: | Amyloid-beta A4 precursor protein-binding family A member 1 |
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| Synonyms: | APBA1_RAT | Apba1 | Mint1 | X11 | neuronal munc18-1 binding protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 92603.32 |
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| Organism: | Rattus norvegicus |
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| Description: | gi_2625023 |
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| Residue: | 839 |
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| Sequence: | MNHLEGSAEVEVADEAPGGEVNESVEADLEHPEVEEEQQPSPPPPAGHAPEDHRAHPAPP
PPPPPQEEEEERGECLARSASTESGFHNHTDTAEGDVLAAARDGYEAERAQDADDESAYA
VQYRPEAEEYTEQAEAEHAEAAQRRALPNHLHFHSLEHEEAMNAAYSGYVYTHRLFHRAE
DEPYAEPYADYGGLQEHVYEEIGDAPELEARDGLRLYERERDEAAAYRQEALGARLHHYD
ERSDGESDSPEKEAEFAPYPRMDSYEQEEDIDQIVAEVKQSMSSQSLDKAAEDMPEAEQD
LERAPTPGGGHPDSPGLPAPAGQQQRVVGTPGGSEVGQRYSKEKRDAISLAIKDIKEAIE
EVKTRTIRSPYTPDEPKEPIWVMRQDISPTRDCDDQRPVDGDSPSPGSSSPLGAESSITP
LHPGDPTEASTNKESRKSLASFPTYVEVPGPCDPEDLIDGIIFAANYLGSTQLLSDKTPS
KNVRMMQAQEAVSRIKTAQKLAKSRKKAPEGESQPMTEVDLFISTQRIKVLNADTQEPMM
DHPLRTISYIADIGNIVVLMARRRMPRSNSQENVEASHPSQDAKRQYKMICHVFESEDAQ
LIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDLLNTQDMYNDDLIHFSKSENCKDVF
IEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLP
LSTCQSIIKGLKNQSRVKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAE
RGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI
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| BDBM54734 |
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| n/a |
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| Name | BDBM54734 |
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| Synonyms: | (Z)-4-(3-nitroanilino)-4-oxo-2-butenoic acid methyl ester | (Z)-4-keto-4-(3-nitroanilino)but-2-enoic acid methyl ester | MLS000723019 | SMR000236409 | cid_12005927 | methyl (Z)-4-(3-nitroanilino)-4-oxobut-2-enoate | methyl (Z)-4-[(3-nitrophenyl)amino]-4-oxidanylidene-but-2-enoate |
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| Type | Small organic molecule |
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| Emp. Form. | C11H10N2O5 |
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| Mol. Mass. | 250.2075 |
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| SMILES | COC(=O)\C=C/C(=O)Nc1cccc(c1)[N+]([O-])=O |
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| Structure | 
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