| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amyloid-beta A4 precursor protein-binding family A member 1 |
|---|
| Ligand | BDBM54747 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | uHTS Homogeneous Terbium Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay |
|---|
| IC50 | 42700±n/a nM |
|---|
| Citation |  PubChem, PC uHTS Homogeneous Terbium Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Amyloid-beta A4 precursor protein-binding family A member 1 |
|---|
| Name: | Amyloid-beta A4 precursor protein-binding family A member 1 |
|---|
| Synonyms: | APBA1_RAT | Apba1 | Mint1 | X11 | neuronal munc18-1 binding protein |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 92603.32 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | gi_2625023 |
|---|
| Residue: | 839 |
|---|
| Sequence: | MNHLEGSAEVEVADEAPGGEVNESVEADLEHPEVEEEQQPSPPPPAGHAPEDHRAHPAPP
PPPPPQEEEEERGECLARSASTESGFHNHTDTAEGDVLAAARDGYEAERAQDADDESAYA
VQYRPEAEEYTEQAEAEHAEAAQRRALPNHLHFHSLEHEEAMNAAYSGYVYTHRLFHRAE
DEPYAEPYADYGGLQEHVYEEIGDAPELEARDGLRLYERERDEAAAYRQEALGARLHHYD
ERSDGESDSPEKEAEFAPYPRMDSYEQEEDIDQIVAEVKQSMSSQSLDKAAEDMPEAEQD
LERAPTPGGGHPDSPGLPAPAGQQQRVVGTPGGSEVGQRYSKEKRDAISLAIKDIKEAIE
EVKTRTIRSPYTPDEPKEPIWVMRQDISPTRDCDDQRPVDGDSPSPGSSSPLGAESSITP
LHPGDPTEASTNKESRKSLASFPTYVEVPGPCDPEDLIDGIIFAANYLGSTQLLSDKTPS
KNVRMMQAQEAVSRIKTAQKLAKSRKKAPEGESQPMTEVDLFISTQRIKVLNADTQEPMM
DHPLRTISYIADIGNIVVLMARRRMPRSNSQENVEASHPSQDAKRQYKMICHVFESEDAQ
LIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDLLNTQDMYNDDLIHFSKSENCKDVF
IEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLP
LSTCQSIIKGLKNQSRVKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAE
RGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI
|
|
|
|---|
| BDBM54747 |
|---|
| n/a |
|---|
| Name | BDBM54747 |
|---|
| Synonyms: | MLS000689387 | N-cyclopentyl-2-(3-keto-4,6-dimethyl-isothiazolo[5,4-b]pyridin-2-yl)acetamide | N-cyclopentyl-2-(4,6-dimethyl-3-oxidanylidene-[1,2]thiazolo[5,4-b]pyridin-2-yl)ethanamide | N-cyclopentyl-2-(4,6-dimethyl-3-oxo-2-isothiazolo[5,4-b]pyridinyl)acetamide | N-cyclopentyl-2-(4,6-dimethyl-3-oxo-[1,2]thiazolo[5,4-b]pyridin-2-yl)acetamide | N-cyclopentyl-2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetamide | SMR000311186 | cid_4048808 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H19N3O2S |
|---|
| Mol. Mass. | 305.395 |
|---|
| SMILES | Cc1cc(C)c2c(n1)sn(CC(=O)NC1CCCC1)c2=O |
|---|
| Structure | 
|
|---|
Search and Browse
