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Reaction Details
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TargetCore protein
LigandBDBM48754
Substrate/Competitorn/a
Meas. Tech.TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50>49751±n/a nM
Citation PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Core protein
Name:Core protein
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:14237.71
Organism:Hepatitis C virus
Description:gi_83779224
Residue:126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRG
RRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVG
KVIDTL
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BDBM48754
n/a
NameBDBM48754
Synonyms:2-(2-chlorophenyl)-N'-(2-keto-5-nitro-indol-3-yl)cinchoninohydrazide | 2-(2-chlorophenyl)-N'-(5-nitro-2-oxidanylidene-indol-3-yl)quinoline-4-carbohydrazide | 2-(2-chlorophenyl)-N'-(5-nitro-2-oxo-3-indolyl)-4-quinolinecarbohydrazide | 2-(2-chlorophenyl)-N'-(5-nitro-2-oxoindol-3-yl)quinoline-4-carbohydrazide | MLS000374708 | SMR000242125 | cid_6283541
TypeSmall organic molecule
Emp. Form.C24H14ClN5O4
Mol. Mass.471.852
SMILES[O-][N+](=O)c1ccc2[N-]C(=O)\C(=[NH+]/NC(=O)c3cc(nc4ccccc34)-c3ccccc3Cl)c2c1
Structure
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