| Reaction Details |
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 | Report a problem with these data |
| Target | 2'-phosphotransferase |
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| Ligand | BDBM50648 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). |
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| IC50 | 13977±n/a nM |
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| Citation |  PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| 2'-phosphotransferase |
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| Name: | 2'-phosphotransferase |
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| Synonyms: | likely tRNA 2'-phosphotransferase |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23631.37 |
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| Organism: | Candida albicans SC5314 |
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| Description: | gi_68476498 |
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| Residue: | 207 |
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| Sequence: | MPPPDKARRDVLISKALSYLLRHGAEKEKLSIDDQGYVKISDVLSHQRLKSLKTTRDDIN
RIVQENDKKRFTIKDDMICANQGHSLKAVKNDNLTPMTVDELNQLRIYHGTYRTKLPLIK
SSGGLSKMNRNHIHFTCEQYSTCSGIRYNANVLIYINASKCIEHGIVFYKSLNNVILTSG
DKDGKLSWEFIDRIVGLDGNEINKEQV
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| BDBM50648 |
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| n/a |
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| Name | BDBM50648 |
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| Synonyms: | MLS000762704 | N-[(5Z)-5-[(E)-3-(2-furanyl)prop-2-enylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]-4-pyridinecarboxamide | N-[(5Z)-5-[(E)-3-(2-furyl)prop-2-enylidene]-4-keto-2-thioxo-thiazolidin-3-yl]isonicotinamide | N-[(5Z)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]pyridine-4-carboxamide | N-[(5Z)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]pyridine-4-carboxamide | N-{5-[(E)-3-Furan-2-yl-prop-2-en-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-isonicotinamide | SMR000438207 | cid_5922856 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H11N3O3S2 |
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| Mol. Mass. | 357.407 |
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| SMILES | O=C(NN1C(=S)S\C(=C/C=C/c2ccco2)C1=O)c1ccncc1 |
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| Structure | 
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