| Reaction Details |
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 | Report a problem with these data |
| Target | 2'-phosphotransferase |
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| Ligand | BDBM55013 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). |
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| IC50 | 274.94±n/a nM |
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| Citation |  PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| 2'-phosphotransferase |
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| Name: | 2'-phosphotransferase |
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| Synonyms: | likely tRNA 2'-phosphotransferase |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23631.37 |
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| Organism: | Candida albicans SC5314 |
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| Description: | gi_68476498 |
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| Residue: | 207 |
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| Sequence: | MPPPDKARRDVLISKALSYLLRHGAEKEKLSIDDQGYVKISDVLSHQRLKSLKTTRDDIN
RIVQENDKKRFTIKDDMICANQGHSLKAVKNDNLTPMTVDELNQLRIYHGTYRTKLPLIK
SSGGLSKMNRNHIHFTCEQYSTCSGIRYNANVLIYINASKCIEHGIVFYKSLNNVILTSG
DKDGKLSWEFIDRIVGLDGNEINKEQV
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|
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| BDBM55013 |
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| n/a |
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| Name | BDBM55013 |
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| Synonyms: | 2-[(5Z)-5-(3-chloro-4-hydroxy-5-methoxy-benzylidene)-2,4-diketo-thiazolidin-3-yl]-N-(2-fluorophenyl)acetamide | 2-[(5Z)-5-[(3-chloranyl-5-methoxy-4-oxidanyl-phenyl)methylidene]-2,4-bis(oxidanylidene)-1,3-thiazolidin-3-yl]-N-(2-fluorophenyl)ethanamide | 2-[(5Z)-5-[(3-chloro-4-hydroxy-5-methoxyphenyl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]-N-(2-fluorophenyl)acetamide | 2-[(5Z)-5-[(3-chloro-4-hydroxy-5-methoxyphenyl)methylidene]-2,4-dioxo-3-thiazolidinyl]-N-(2-fluorophenyl)acetamide | 2-[5-(3-chloro-4-hydroxy-5-methoxybenzylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]-N-(2-fluorophenyl)acetamide | MLS000974649 | SMR000497148 | cid_1322017 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H14ClFN2O5S |
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| Mol. Mass. | 436.841 |
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| SMILES | COc1cc(\C=C2/SC(=O)N(CC(=O)Nc3ccccc3F)C2=O)cc(Cl)c1O |
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| Structure | 
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