| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Genome polyprotein |
|---|
| Ligand | BDBM53463 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay for inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3). |
|---|
| IC50 | 5413±n/a nM |
|---|
| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3). PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Genome polyprotein |
|---|
| Name: | Genome polyprotein |
|---|
| Synonyms: | NS3 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 67067.41 |
|---|
| Organism: | Hepatitis C virus |
|---|
| Description: | gi_125541954 |
|---|
| Residue: | 631 |
|---|
| Sequence: | APITAYAQQTRGLLGCIITGLTGRDKNQVEGEVQIVSTAAQTFLATCINGVCWTVYHGAG
TRTIASSKGPVIQMYTNVDQDLVGWPAPQGARSLTPCTCGSSDLYLVTRHADVIPVRRRG
DGRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRAAVCTRGVAKAVDFIPVEGLETTMR
SPVFSDNSSPPAVPQSYQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGA
YMSKAHGIDPNIRTGVRTITTGSPITYSTYGKFLADGGCSGSAYDIIICDECHSTDATSI
LGIGTVLDQAETAGARLTVLATATPPGSVTVPHPNIEEVALSTTGEIPFYGKAIPLEAIK
GGRHLIFCHSKKKCDELAAKLVALGVNAVAYYRGLDVSVIPASGDVVVVATDALMTGFTG
DFDSVIDCNTCVTQTVDFSLDPTFTIETTTLPQDAVSRTQRRGRTGRGKPGIYRFVTPGE
RPSGMFDSSVLCECYDAGCAWYELTPAETTVRLRAYMNTPGLPVCQDHLEFWEGVFTGLT
HIDAHFLSQTKQSGENLPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLY
RLGAVQNEITLTHPITKYIMTCMSADLEVVT
|
|
|
|---|
| BDBM53463 |
|---|
| n/a |
|---|
| Name | BDBM53463 |
|---|
| Synonyms: | 1-[[4-(1-adamantyl)phenyl]methylideneamino]thiourea | 4-(1-adamantyl)benzaldehyde thiosemicarbazone | MLS001000567 | O-acyl oxime isatin derivative, 45 | SMR000496110 | [[4-(1-adamantyl)benzylidene]amino]thiourea | [[4-(1-adamantyl)phenyl]methylideneamino]thiourea | cid_2839927 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H23N3S |
|---|
| Mol. Mass. | 313.46 |
|---|
| SMILES | [H]C12CC3([H])CC([H])(C1)CC(C2)(C3)c1ccc(C=NNC(N)=S)cc1 |w:18.21,TLB:8:1:12:6.9.5,8:6:12:1.11.2,THB:5:6:11:3.12.2| |
|---|
| Structure | 
|
|---|
Search and Browse
