| Reaction Details |
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 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 4 [Q124R] |
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| Ligand | BDBM55087 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Modulation of the Metabotropic Glutamate Receptor mGluR4: Rat PAM Potency |
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| EC50 | 30±n/a nM |
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| Citation |  PubChem, PC Modulation of the Metabotropic Glutamate Receptor mGluR4: Rat PAM Potency PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Metabotropic glutamate receptor 4 [Q124R] |
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| Name: | Metabotropic glutamate receptor 4 [Q124R] |
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| Synonyms: | GRM4_RAT | Gprc1d | Grm4 | Mglur4 | glutamate receptor, metabotropic 4 precursor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 101878.86 |
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| Organism: | Rattus norvegicus |
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| Description: | gi_12083595 |
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| Residue: | 912 |
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| Sequence: | MSGKGGWAWWWARLPLCLLLSLYAPWVPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGR
GSEGKACGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL
TFVRALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA
STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTLASEGSYGESGVEAFIQ
KSRENGGVCIAQSVKIPREPKTGEFDKIIKRLLETSNARGIIIFANEDDIRRVLEAARRA
NQTGHFFWMGSDSWGSKSAPVLRLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNI
WFAEFWEDNFHCKLSRHALKKGSHIKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL
HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQY
QLRNGSAEYKVIGSWTDHLHLRIERMQWPGSGQQLPRSICSLPCQPGERKKTVKGMACCW
HCEPCTGYQYQVDRYTCKTCPYDMRPTENRTSCQPIPIVKLEWDSPWAVLPLFLAVVGIA
ATLFVVVTFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLG
LGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFILISLQLLGICVWFVV
DPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPET
FNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMP
KVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLETPALAT
KQTYVTYTNHAI
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| BDBM55087 |
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| n/a |
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| Name | BDBM55087 |
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| Synonyms: | N-[3-chloranyl-4-[4-chloranyl-1,3-bis(oxidanylidene)isoindol-2-yl]phenyl]pyridine-2-carboxamide | N-[3-chloro-4-(4-chloro-1,3-diketo-isoindolin-2-yl)phenyl]picolinamide | N-[3-chloro-4-(4-chloro-1,3-dioxo-2-isoindolyl)phenyl]-2-pyridinecarboxamide | N-[3-chloro-4-(4-chloro-1,3-dioxoisoindol-2-yl)phenyl]pyridine-2-carboxamide | VU0405623-1 | cid_46869944 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H11Cl2N3O3 |
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| Mol. Mass. | 412.226 |
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| SMILES | Clc1cccc2C(=O)N(C(=O)c12)c1ccc(NC(=O)c2ccccn2)cc1Cl |
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| Structure | 
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