Ki Summary

Reaction Details

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Target

M18 aspartyl aminopeptidase

Ligand

BDBM55109

Substrate/Competitor

n/a

Meas. Tech.

QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP).

IC50

350.82±n/a nM

Citation

PubChem, PC QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP). PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

M18 aspartyl aminopeptidase

Name:

M18 aspartyl aminopeptidase

Synonyms:

n/a

Type:

Enzyme Catalytic Domain

Mol. Mass.:

65642.43

Organism:

Plasmodium falciparum 3D7

Description:

gi_23505220

Residue:

570

Sequence:

MDKKAREYAQDALKFIQRSGSNFLACKNLKERLENNGFINLSEGETWNLNKNEGYVLCKE
NRNICGFFVGKNFNIDTGSILISIGHIDSCALKISPNNNVIKKKIHQINVECYGSGLWHT
WFDRSLGLSGQVLYKKGNKLVEKLIQINKSVLFLPSLAIHLQNRTRYDFSVKINYENHIK
PIISTTLFNQLNKCKRNNVHHDTILTTDTKFSHKENSQNKRDDQMCHSFNDKDVSNHNLD
KNTIEHLTNQQNEEKNKHTKDNPNSKDIVEHINTDNSYPLLYLLSKELNCKEEDILDFEL
CLMDTQEPCFTGVYEEFIEGARFDNLLGSFCVFEGFIELVNSIKNHTSNENTNHTNNITN
DINDNIHNNLYISIGYDHEEIGSLSEVGARSYCTKNFIDRIISSVFKKEIHEKNLSVQEI
YGNLVNRSFILNVDMAHCSHPNYPETVQDNHQLFFHEGIAIKYNTNKNYVTSPLHASLIK
RTFELYYNKYKQQIKYQNFMVKNDTPCGSTVGSMVAANLSMPGIDIGIPQLAMHSIREIA
AVHDVFFLIKGVFAFYTYYNQVLSTCVHDK

BDBM55109

n/a

Name

BDBM55109

Synonyms:

2-[(4-methylphenyl)sulfonyl-(1,2,4-triazol-4-yl)amino]acetic acid methyl ester | 2-[tosyl(1,2,4-triazol-4-yl)amino]acetic acid methyl ester | MLS000052573 | SMR000082082 | cid_918926 | methyl 2-[(4-methylphenyl)sulfonyl-(1,2,4-triazol-4-yl)amino]acetate | methyl 2-[(4-methylphenyl)sulfonyl-(1,2,4-triazol-4-yl)amino]ethanoate | methyl N-[(4-methylphenyl)sulfonyl]-N-4H-1,2,4-triazol-4-ylglycinate

Type

Small organic molecule

Emp. Form.

C12H14N4O4S

Mol. Mass.

310.329

SMILES

COC(=O)CN(n1cnnc1)S(=O)(=O)c1ccc(C)cc1

Structure