Reaction Details | |||
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Target | Neutrophil cytosol factor 1 [S99G] | ||
Ligand | BDBM38875 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) | ||
IC50 | 1420±n/a nM | ||
Citation | PubChem, PC Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) PubChem Bioassay(2008)[AID] | ||
More Info.: | Get all data from this article, Solution Info, Assay Method | ||
Neutrophil cytosol factor 1 [S99G] | |||
Name: | Neutrophil cytosol factor 1 [S99G] | ||
Synonyms: | NCF1 | NCF1_HUMAN | NOXO2 | SH3PXD1A | neutrophil cytosolic factor 1 | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 44664.39 | ||
Organism: | Homo sapiens (Human) | ||
Description: | gi_115298672 | ||
Residue: | 390 | ||
Sequence: |
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BDBM38875 | |||
n/a | |||
Name | BDBM38875 | ||
Synonyms: | 2-(5-spiro[3H-benzimidazole-2,1'-cyclohexane]ylidene)propanedinitrile | 2-spiro[3H-benzimidazole-2,1'-cyclohexane]-5-ylidenemalononitrile | 2-spiro[3H-benzimidazole-2,1'-cyclohexane]-5-ylidenepropanedinitrile | MLS000038588 | SMR000038412 | cid_657611 | ||
Type | Small organic molecule | ||
Emp. Form. | C15H14N4 | ||
Mol. Mass. | 250.2985 | ||
SMILES | N#CC(C#N)=c1ccc2=NC3(CCCCC3)Nc2c1 |t:8,(7.69,6.11,;6.92,4.78,;6.16,3.44,;4.62,3.43,;3.08,3.43,;6.94,2.11,;8.54,2.11,;9.33,.71,;8.51,-.66,;8.98,-2.13,;7.74,-3.03,;9.07,-3.8,;9.07,-5.34,;7.74,-6.11,;6.4,-5.34,;6.4,-3.8,;6.49,-2.13,;6.97,-.66,;6.14,.71,)| | ||
Structure |