| Reaction Details |
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 | Report a problem with these data |
| Target | Neutrophil cytosol factor 1 [S99G] |
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| Ligand | BDBM41826 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) |
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| IC50 | 3730±n/a nM |
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| Citation |  PubChem, PC Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Neutrophil cytosol factor 1 [S99G] |
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| Name: | Neutrophil cytosol factor 1 [S99G] |
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| Synonyms: | NCF1 | NCF1_HUMAN | NOXO2 | SH3PXD1A | neutrophil cytosolic factor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44664.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_115298672 |
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| Residue: | 390 |
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| Sequence: | MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPI
EAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKV
RPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTG
DVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAV
EGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPP
RRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSK
PQPAVPPRPSADLILNRCSESTKRKLASAV
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| BDBM41826 |
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| n/a |
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| Name | BDBM41826 |
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| Synonyms: | 2-[[(4E)-1-keto-4-(2-thienylsulfonylimino)-2-naphthyl]amino]benzoic acid methyl ester | 2-[[(4E)-1-oxo-4-thiophen-2-ylsulfonylimino-2-naphthalenyl]amino]benzoic acid methyl ester | MLS000521465 | SMR000131873 | cid_9550941 | methyl 2-[[(4E)-1-oxidanylidene-4-thiophen-2-ylsulfonylimino-naphthalen-2-yl]amino]benzoate | methyl 2-[[(4E)-1-oxo-4-thiophen-2-ylsulfonyliminonaphthalen-2-yl]amino]benzoate |
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| Type | Small organic molecule |
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| Emp. Form. | C22H16N2O5S2 |
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| Mol. Mass. | 452.503 |
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| SMILES | COC(=O)c1ccccc1NC1=CC(=NS(=O)(=O)c2cccs2)c2ccccc2C1=O |w:14.15,t:12| |
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| Structure | 
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