| Reaction Details |
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 | Report a problem with these data |
| Target | Neutrophil cytosol factor 1 [S99G] |
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| Ligand | BDBM55547 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) |
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| IC50 | 2110±n/a nM |
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| Citation |  PubChem, PC Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Neutrophil cytosol factor 1 [S99G] |
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| Name: | Neutrophil cytosol factor 1 [S99G] |
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| Synonyms: | NCF1 | NCF1_HUMAN | NOXO2 | SH3PXD1A | neutrophil cytosolic factor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44664.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_115298672 |
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| Residue: | 390 |
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| Sequence: | MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPI
EAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKV
RPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTG
DVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAV
EGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPP
RRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSK
PQPAVPPRPSADLILNRCSESTKRKLASAV
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| BDBM55547 |
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| n/a |
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| Name | BDBM55547 |
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| Synonyms: | (4Z)-4-[[5-(2-nitrophenyl)-2-furanyl]methylidene]-3-phenyl-5-isoxazolone | (4Z)-4-[[5-(2-nitrophenyl)-2-furyl]methylene]-3-phenyl-2-isoxazolin-5-one | (4Z)-4-[[5-(2-nitrophenyl)furan-2-yl]methylidene]-3-phenyl-1,2-oxazol-5-one | 4-{[5-(2-nitrophenyl)-2-furyl]methylene}-3-phenyl-5(4H)-isoxazolone | MLS000576682 | SMR000197150 | cid_2301119 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H12N2O5 |
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| Mol. Mass. | 360.3197 |
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| SMILES | [O-][N+](=O)c1ccccc1-c1ccc([CH+]c2c([n-]oc2=O)-c2ccccc2)o1 |
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| Structure | 
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