| Reaction Details |
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 | Report a problem with these data |
| Target | Neutrophil cytosol factor 1 [S99G] |
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| Ligand | BDBM34786 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) |
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| IC50 | 4180±n/a nM |
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| Citation |  PubChem, PC Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Neutrophil cytosol factor 1 [S99G] |
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| Name: | Neutrophil cytosol factor 1 [S99G] |
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| Synonyms: | NCF1 | NCF1_HUMAN | NOXO2 | SH3PXD1A | neutrophil cytosolic factor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44664.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_115298672 |
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| Residue: | 390 |
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| Sequence: | MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPI
EAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKV
RPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTG
DVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAV
EGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPP
RRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSK
PQPAVPPRPSADLILNRCSESTKRKLASAV
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| BDBM34786 |
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| n/a |
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| Name | BDBM34786 |
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| Synonyms: | 3-(4-methylphenyl)-2-phenyl-1,2,4-thiadiazol-2-ium-5-amine;bromide | MLS000722022 | SMR000236708 | [2-phenyl-3-(p-tolyl)-1,2,4-thiadiazol-2-ium-5-yl]amine;bromide | cid_12005893 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14N3S |
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| Mol. Mass. | 268.356 |
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| SMILES | Cc1ccc(cc1)-c1nc(N)s[n+]1-c1ccccc1 |
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| Structure | 
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