| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neutrophil cytosol factor 1 [S99G] |
|---|
| Ligand | BDBM55707 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) |
|---|
| IC50 | 5330±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Neutrophil cytosol factor 1 [S99G] |
|---|
| Name: | Neutrophil cytosol factor 1 [S99G] |
|---|
| Synonyms: | NCF1 | NCF1_HUMAN | NOXO2 | SH3PXD1A | neutrophil cytosolic factor 1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44664.39 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_115298672 |
|---|
| Residue: | 390 |
|---|
| Sequence: | MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPI
EAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKV
RPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTG
DVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAV
EGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPP
RRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSK
PQPAVPPRPSADLILNRCSESTKRKLASAV
|
|
|
|---|
| BDBM55707 |
|---|
| n/a |
|---|
| Name | BDBM55707 |
|---|
| Synonyms: | MLS000682564 | N-[3-(4-ethyl-1-piperazinyl)propyl]-4-[(E)-[4-[(2-fluorophenyl)methyl]-3-oxo-1,4-benzothiazin-2-ylidene]methyl]benzamide | N-[3-(4-ethylpiperazin-1-yl)propyl]-4-[(E)-[4-[(2-fluorophenyl)methyl]-3-oxidanylidene-1,4-benzothiazin-2-ylidene]methyl]benzamide | N-[3-(4-ethylpiperazin-1-yl)propyl]-4-[(E)-[4-[(2-fluorophenyl)methyl]-3-oxo-1,4-benzothiazin-2-ylidene]methyl]benzamide | N-[3-(4-ethylpiperazin-1-yl)propyl]-4-{(E)-[4-(2-fluorobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-ylidene]methyl}benzamide | N-[3-(4-ethylpiperazino)propyl]-4-[(E)-[4-(2-fluorobenzyl)-3-keto-1,4-benzothiazin-2-ylidene]methyl]benzamide | SMR000311921 | cid_16189324 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C32H35FN4O2S |
|---|
| Mol. Mass. | 558.709 |
|---|
| SMILES | CCN1CCN(CCCNC(=O)c2ccc(\C=C3\Sc4ccccc4N(Cc4ccccc4F)C3=O)cc2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
