| Reaction Details |
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 | Report a problem with these data |
| Target | Neutrophil cytosol factor 1 [S99G] |
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| Ligand | BDBM33200 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) |
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| IC50 | 10430±n/a nM |
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| Citation |  PubChem, PC Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Neutrophil cytosol factor 1 [S99G] |
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| Name: | Neutrophil cytosol factor 1 [S99G] |
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| Synonyms: | NCF1 | NCF1_HUMAN | NOXO2 | SH3PXD1A | neutrophil cytosolic factor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44664.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_115298672 |
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| Residue: | 390 |
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| Sequence: | MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPI
EAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKV
RPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTG
DVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAV
EGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPP
RRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSK
PQPAVPPRPSADLILNRCSESTKRKLASAV
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| BDBM33200 |
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| n/a |
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| Name | BDBM33200 |
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| Synonyms: | 2-(2-furanyl)-4-quinolinecarboxylic acid [2-(diethylamino)-2-oxoethyl] ester | 2-(2-furyl)cinchoninic acid [2-(diethylamino)-2-keto-ethyl] ester | MLS000772521 | SMR000377201 | [2-(diethylamino)-2-oxidanylidene-ethyl] 2-(furan-2-yl)quinoline-4-carboxylate | [2-(diethylamino)-2-oxoethyl] 2-(furan-2-yl)quinoline-4-carboxylate | cid_2096417 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20N2O4 |
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| Mol. Mass. | 352.3838 |
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| SMILES | CCN(CC)C(=O)COC(=O)c1cc(nc2ccccc12)-c1ccco1 |
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| Structure | 
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