| Reaction Details |
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 | Report a problem with these data |
| Target | Neutrophil cytosol factor 1 [S99G] |
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| Ligand | BDBM50605 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) |
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| IC50 | 4640±n/a nM |
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| Citation |  PubChem, PC Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Neutrophil cytosol factor 1 [S99G] |
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| Name: | Neutrophil cytosol factor 1 [S99G] |
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| Synonyms: | NCF1 | NCF1_HUMAN | NOXO2 | SH3PXD1A | neutrophil cytosolic factor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44664.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_115298672 |
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| Residue: | 390 |
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| Sequence: | MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPI
EAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKV
RPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTG
DVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAV
EGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPP
RRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSK
PQPAVPPRPSADLILNRCSESTKRKLASAV
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| BDBM50605 |
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| n/a |
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| Name | BDBM50605 |
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| Synonyms: | 2,3-Dichloro-5,8-dimethoxy-[1,4]naphthoquinone | 2,3-bis(chloranyl)-5,8-dimethoxy-naphthalene-1,4-dione | 2,3-dichloro-5,8-dimethoxy-1,4-naphthoquinone | 2,3-dichloro-5,8-dimethoxynaphthalene-1,4-dione | MLS001030189 | SMR000425588 | cid_375895 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H8Cl2O4 |
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| Mol. Mass. | 287.096 |
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| SMILES | COc1ccc(OC)c2C(=O)C(Cl)=C(Cl)C(=O)c12 |t:12| |
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| Structure | 
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