| Reaction Details |
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 | Report a problem with these data |
| Target | Streptokinase A |
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| Ligand | BDBM58058 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression |
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| EC50 | 150000±n/a nM |
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| Citation |  PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Streptokinase A |
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| Name: | Streptokinase A |
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| Synonyms: | STRP_STRP1 | ska | streptokinase A precursor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49924.80 |
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| Organism: | Streptococcus pyogenes M1 GAS |
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| Description: | gi_15675770 |
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| Residue: | 440 |
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| Sequence: | MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVF
INFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSN
DGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQ
AKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGY
TIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKY
YVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAK
LLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEER
KAYSYLRDTGTPIPDNPKDK
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|
|
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| BDBM58058 |
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| n/a |
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| Name | BDBM58058 |
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| Synonyms: | 2-methyl-3-[[(E)-(1-oxidanylidenenaphthalen-2-ylidene)methyl]amino]quinazolin-4-one | 2-methyl-3-[[(E)-(1-oxo-2-naphthalenylidene)methyl]amino]-4-quinazolinone | 2-methyl-3-[[(E)-(1-oxonaphthalen-2-ylidene)methyl]amino]quinazolin-4-one | 3-[[(E)-(1-keto-2-naphthylidene)methyl]amino]-2-methyl-quinazolin-4-one | 3-{[1-(1-Hydroxy-naphthalen-2-yl)-meth-(E)-ylidene]-amino}-2-methyl-3H-quinazolin-4-one | MLS000777338 | SMR000413723 | cid_5423268 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H15N3O2 |
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| Mol. Mass. | 329.352 |
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| SMILES | Cc1nc2ccccc2c(=O)n1N=Cc1ccc2ccccc2c1O |w:12.13| |
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| Structure | 
|
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