Ki Summary

Reaction Details

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Target

Streptokinase A

Ligand

BDBM50633

Substrate/Competitor

n/a

Meas. Tech.

Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression

EC50

150000±n/a nM

Citation

PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Streptokinase A

Name:

Streptokinase A

Synonyms:

STRP_STRP1 | ska | streptokinase A precursor

Type:

Enzyme Catalytic Domain

Mol. Mass.:

49924.80

Organism:

Streptococcus pyogenes M1 GAS

Description:

gi_15675770

Residue:

440

Sequence:

MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVF
INFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSN
DGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQ
AKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGY
TIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKY
YVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAK
LLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEER
KAYSYLRDTGTPIPDNPKDK

BDBM50633

n/a

Name

BDBM50633

Synonyms:

4-Methyl-N-{5-[(E)-2-methyl-3-phenyl-prop-2-en-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-benzenesulf onamide | 4-methyl-N-[(5Z)-5-[(E)-2-methyl-3-phenyl-prop-2-enylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]benzenesulfonamide | 4-methyl-N-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzenesulfonamide | 4-methyl-N-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]benzenesulfonamide | MLS000778611 | N-[(5Z)-4-keto-5-[(E)-2-methyl-3-phenyl-prop-2-enylidene]-2-thioxo-thiazolidin-3-yl]-4-methyl-benzenesulfonamide | SMR000415405 | cid_2048896

Type

Small organic molecule

Emp. Form.

C20H18N2O3S3

Mol. Mass.

430.564

SMILES

C\C(\C=C1/SC(=S)N(NS(=O)(=O)c2ccc(C)cc2)C1=O)=C/c1ccccc1

Structure