Ki Summary

Reaction Details

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Target

Streptokinase A

Ligand

BDBM58074

Substrate/Competitor

n/a

Meas. Tech.

Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression

EC50

150000±n/a nM

Citation

PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Streptokinase A

Name:

Streptokinase A

Synonyms:

STRP_STRP1 | ska | streptokinase A precursor

Type:

Enzyme Catalytic Domain

Mol. Mass.:

49924.80

Organism:

Streptococcus pyogenes M1 GAS

Description:

gi_15675770

Residue:

440

Sequence:

MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVF
INFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSN
DGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQ
AKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGY
TIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKY
YVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAK
LLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEER
KAYSYLRDTGTPIPDNPKDK

BDBM58074

n/a

Name

BDBM58074

Synonyms:

2-N-(3-chlorophenyl)-4-N-(furan-2-ylmethyl)-5-nitropyrimidine-2,4,6-triamine | MLS000333252 | N-(3-Chloro-phenyl)-N'-furan-2-ylmethyl-5-nitro-pyrimidine-2,4,6-triamine | N2-(3-chlorophenyl)-N4-(2-furanylmethyl)-5-nitropyrimidine-2,4,6-triamine | N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)-5-nitro-pyrimidine-2,4,6-triamine | SMR000436516 | [6-amino-2-(3-chloroanilino)-5-nitro-pyrimidin-4-yl]-(2-furfuryl)amine | cid_4360053

Type

Small organic molecule

Emp. Form.

C15H13ClN6O3

Mol. Mass.

360.755

SMILES

Nc1nc(Nc2cccc(Cl)c2)nc(NCc2ccco2)c1[N+]([O-])=O

Structure