| Reaction Details |
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 | Report a problem with these data |
| Target | Streptokinase A |
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| Ligand | BDBM58076 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression |
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| EC50 | 6954±n/a nM |
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| Citation |  PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Streptokinase A |
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| Name: | Streptokinase A |
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| Synonyms: | STRP_STRP1 | ska | streptokinase A precursor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49924.80 |
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| Organism: | Streptococcus pyogenes M1 GAS |
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| Description: | gi_15675770 |
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| Residue: | 440 |
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| Sequence: | MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVF
INFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSN
DGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQ
AKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGY
TIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKY
YVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAK
LLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEER
KAYSYLRDTGTPIPDNPKDK
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|
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| BDBM58076 |
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| n/a |
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| Name | BDBM58076 |
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| Synonyms: | (5-Isopropyl-2-methyl-3-phenyl-pyrazolo[1,5-a]pyrimidin-7-yl)-pyridin-2-ylmethyl-amine | (5-isopropyl-2-methyl-3-phenyl-pyrazolo[1,5-a]pyrimidin-7-yl)-(2-pyridylmethyl)amine | 2-methyl-3-phenyl-5-propan-2-yl-N-(2-pyridinylmethyl)-7-pyrazolo[1,5-a]pyrimidinamine | 2-methyl-3-phenyl-5-propan-2-yl-N-(pyridin-2-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine | MLS000762881 | SMR000439709 | cid_1966501 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H23N5 |
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| Mol. Mass. | 357.4515 |
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| SMILES | CC(C)c1cc(NCc2ccccn2)n2nc(C)c(-c3ccccc3)c2n1 |
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| Structure | 
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