| Reaction Details |
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 | Report a problem with these data |
| Target | Streptokinase A |
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| Ligand | BDBM50006805 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression |
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| EC50 | 1237±n/a nM |
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| Citation |  PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Streptokinase A |
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| Name: | Streptokinase A |
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| Synonyms: | STRP_STRP1 | ska | streptokinase A precursor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49924.80 |
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| Organism: | Streptococcus pyogenes M1 GAS |
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| Description: | gi_15675770 |
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| Residue: | 440 |
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| Sequence: | MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVF
INFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSN
DGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQ
AKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGY
TIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKY
YVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAK
LLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEER
KAYSYLRDTGTPIPDNPKDK
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|
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| BDBM50006805 |
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| n/a |
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| Name | BDBM50006805 |
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| Synonyms: | 3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isopropyl-1H-indol-2-yl)-2,2-dimethylpropanoic acid | 3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-isopropyl-1H-indol-2-yl)-2,2-dimethylpropanoic acid | 3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid | 3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-isopropyl-1H-indol-2-yl]-2,2-dimethyl-propionic acid | CHEMBL29097 | MK-886 | MK886 | cid_3651377 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H34ClNO2S |
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| Mol. Mass. | 472.082 |
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| SMILES | CC(C)c1ccc2n(Cc3ccc(Cl)cc3)c(CC(C)(C)C(O)=O)c(SC(C)(C)C)c2c1 |
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| Structure | 
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