| Reaction Details |
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 | Report a problem with these data |
| Target | Streptokinase A |
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| Ligand | BDBM58922 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression |
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| EC50 | 3408±n/a nM |
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| Citation |  PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Streptokinase A |
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| Name: | Streptokinase A |
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| Synonyms: | STRP_STRP1 | ska | streptokinase A precursor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49924.80 |
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| Organism: | Streptococcus pyogenes M1 GAS |
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| Description: | gi_15675770 |
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| Residue: | 440 |
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| Sequence: | MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVF
INFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSN
DGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQ
AKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGY
TIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKY
YVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAK
LLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEER
KAYSYLRDTGTPIPDNPKDK
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| BDBM58922 |
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| n/a |
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| Name | BDBM58922 |
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| Synonyms: | MLS001304727 | MONTELUKAST Na | SMR000469188 | cid_23663996 | sodium;2-[1-[[(1R)-1-[3-[(E)-2-(7-chloranylquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-oxidanylpropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]ethanoate | sodium;2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetate | sodium;2-[1-[[[(1R)-1-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]thio]methyl]cyclopropyl]acetate | sodium;2-[1-[[[(1R)-1-[3-[(E)-2-(7-chloro-2-quinolyl)vinyl]phenyl]-3-[2-(1-hydroxy-1-methyl-ethyl)phenyl]propyl]thio]methyl]cyclopropyl]acetate |
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| Type | Small organic molecule |
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| Emp. Form. | C35H35ClNO3S |
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| Mol. Mass. | 585.176 |
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| SMILES | CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC([O-])=O)CC1)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 |
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| Structure | 
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