| Reaction Details |
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 | Report a problem with these data |
| Target | Large T antigen |
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| Ligand | BDBM58949 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Identification of SV40 T antigen inhibitors: Cytotoxicity screen of selected hits |
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| EC50 | >50000±n/a nM |
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| Citation |  PubChem, PC Identification of SV40 T antigen inhibitors: Cytotoxicity screen of selected hits PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Large T antigen |
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| Name: | Large T antigen |
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| Synonyms: | LT | LT-AG | LT_SV40 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 81575.54 |
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| Organism: | Simian virus 40 |
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| Description: | P03070 |
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| Residue: | 708 |
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| Sequence: | MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYK
KMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADS
QHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYS
VTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDP
FSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFE
MCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQM
LTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKR
YWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGG
ESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQAR
FVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWK
ERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHE
TGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET
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| BDBM58949 |
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| n/a |
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| Name | BDBM58949 |
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| Synonyms: | MLS000033552 | N-(4-Dimethylamino-phenyl)-2-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-acetamide | N-[4-(dimethylamino)phenyl]-2-[4-(4-fluorobenzoyl)piperidin-1-yl]acetamide | N-[4-(dimethylamino)phenyl]-2-[4-(4-fluorobenzoyl)piperidino]acetamide | N-[4-(dimethylamino)phenyl]-2-[4-(4-fluorophenyl)carbonylpiperidin-1-yl]ethanamide | N-[4-(dimethylamino)phenyl]-2-[4-[(4-fluorophenyl)-oxomethyl]-1-piperidinyl]acetamide | SMR000007080 | cid_656006 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H26FN3O2 |
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| Mol. Mass. | 383.4591 |
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| SMILES | CN(C)c1ccc(NC(=O)CN2CCC(CC2)C(=O)c2ccc(F)cc2)cc1 |
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| Structure | 
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