| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Large T antigen |
|---|
| Ligand | BDBM32135 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Identification of SV40 T antigen inhibitors: Cytotoxicity screen of selected hits |
|---|
| EC50 | >50000±n/a nM |
|---|
| Citation |  PubChem, PC Identification of SV40 T antigen inhibitors: Cytotoxicity screen of selected hits PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Large T antigen |
|---|
| Name: | Large T antigen |
|---|
| Synonyms: | LT | LT-AG | LT_SV40 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 81575.54 |
|---|
| Organism: | Simian virus 40 |
|---|
| Description: | P03070 |
|---|
| Residue: | 708 |
|---|
| Sequence: | MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYK
KMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADS
QHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYS
VTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDP
FSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFE
MCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQM
LTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKR
YWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGG
ESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQAR
FVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWK
ERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHE
TGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET
|
|
|
|---|
| BDBM32135 |
|---|
| n/a |
|---|
| Name | BDBM32135 |
|---|
| Synonyms: | 4-[4-(3,4-dihydroxyphenyl)-3H-1,3-thiazol-2-ylidene]cyclohexa-2,5-dien-1-one | 4-[4-(3,4-dihydroxyphenyl)-3H-thiazol-2-ylidene]-1-cyclohexa-2,5-dienone | 4-[4-(3,4-dihydroxyphenyl)-4-thiazolin-2-ylidene]cyclohexa-2,5-dien-1-one | 4-[4-[3,4-bis(oxidanyl)phenyl]-3H-1,3-thiazol-2-ylidene]cyclohexa-2,5-dien-1-one | MLS000111214 | SMR000107140 | cid_5406370 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H11NO3S |
|---|
| Mol. Mass. | 285.318 |
|---|
| SMILES | Oc1ccc(cc1)-c1nc(cs1)-c1ccc(O)c(O)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
